![]() The project builds on previous research that Brown and her colleagues conducted into a different disease model: sepsis. The National Institute on Aging-a division of the National Institutes of Health-is awarding WVU $2,687,415 for the five-year project. Their findings could even point to therapeutics for other age-related disorders. What they learn could indicate a potential target for medications that improve how the brain’s blood vessels function after a stroke. To fill this knowledge gap, Brown and her colleagues are exploring how a specific enzyme protects the brain from the effects of stroke and aging. It’s more rigorous and translates better to the real world.” “That doesn’t really mimic the person who gets a stroke,” said Candice Brown, a researcher with the West Virginia University School of Medicine and Rockefeller Neuroscience Institute. ![]() Yet historically, most stroke studies involving animal models have focused on young test subjects, not older ones. About two-thirds of the people hospitalized for one are at least 65 years old, according to the Centers for Disease Control. Although strokes can occur no matter how old you are, your risk for one increases as you age.
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